The study was large. The larger the study, the more likely it is that the results are applicable to the population in general. Think of flipping a coin; the more times you flip it, the more likely you are to have gotten heads half the time and tails half the time. Many skincare studies have only five or ten participants, which is unfortunate. I give far less weight to these than to studies with thirty or more subjects.The study was large. The larger the study, the more likely it is that the results are applicable to the population in general. Think of flipping a coin; the more times you flip it, the more likely you are to have gotten heads half the time and tails half the time. Many skincare studies have only five or ten participants, which is unfortunate. I give far less weight to these than to studies with thirty or more subjects.